The role of SNARE proteins in trafficking and function of neurotransmitter transporters.

@article{Quick2006TheRO,
  title={The role of SNARE proteins in trafficking and function of neurotransmitter transporters.},
  author={Michael W. Quick},
  journal={Handbook of experimental pharmacology},
  year={2006},
  volume={175},
  pages={181-96}
}
The SNARE hypothesis of vesicle fusion proposes that a series of protein-protein interactions governs the delivery of vesicles to various membrane targets such as the Golgi network and the plasma membrane. Key players in this process include members of the syntaxin family of membrane proteins. The first member identified in this family, syntaxin 1A, plays an essential role in the docking and fusion of neurotransmitter-containing vesicles to the presynaptic membrane of neurons. Syntaxin 1A and… CONTINUE READING
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