The role of RNA alternative splicing in regulating cancer metabolism

Abstract

Tumor cells alter their metabolism by a wide array of mechanisms to promote growth and proliferation. Dysregulated expression and/or somatic mutations of key components of the glycolytic pathway/TCA cycle as well as other metabolic pathways allow tumor cells to improve their ability to survive harsh conditions such as hypoxia and the presence of reactive… (More)
DOI: 10.1007/s00439-017-1803-x

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Cite this paper

@article{Kozlovski2017TheRO, title={The role of RNA alternative splicing in regulating cancer metabolism}, author={Itamar Kozlovski and Zahava Siegfried and Adi Amar-Schwartz and Rotem Karni}, journal={Human Genetics}, year={2017}, volume={136}, pages={1113-1127} }