The role of PerR in O2-affected gene expression of Clostridium acetobutylicum.

@article{Hillmann2009TheRO,
  title={The role of PerR in O2-affected gene expression of Clostridium acetobutylicum.},
  author={Falk Hillmann and Christina D{\"o}ring and Oliver Riebe and Armin Ehrenreich and Ralf-J{\"o}rg Fischer and Hubert Bahl},
  journal={Journal of bacteriology},
  year={2009},
  volume={191 19},
  pages={
          6082-93
        }
}
In the strict anaerobe Clostridium acetobutylicum, a PerR-homologous protein has recently been identified as being a key repressor of a reductive machinery for the scavenging of reactive oxygen species and molecular O(2). In the absence of PerR, the full derepression of its regulon resulted in increased resistance to oxidative stress and nearly full tolerance of an aerobic environment. In the present study, the complementation of a Bacillus subtilis PerR mutant confirmed that the homologous… CONTINUE READING
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