The role of PPARgamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunction.

Abstract

BACKGROUND & AIMS Psychological stress has been implicated in the clinical course of several gastrointestinal diseases, but the mechanisms implicated and the effects of stress on the normal colon are not yet fully understood. METHODS Male Wistar rats were exposed to various immobilization periods as a stress paradigm. Colon was processed to assess… (More)

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