The role of NO in macrophage dysfunction at early stage after burn injury.

@article{Luo2005TheRO,
  title={The role of NO in macrophage dysfunction at early stage after burn injury.},
  author={Gaoxing Luo and Daizhi Peng and Junsong Zheng and Xiwei Chen and Jingjing Wu and Eric A. Elster and Douglas K. Tadaki},
  journal={Burns : journal of the International Society for Burn Injuries},
  year={2005},
  volume={31 2},
  pages={
          138-44
        }
}
AIM To explore the role of nitric oxide (NO) in macrophage dysfunction at early stage after burn injury. METHOD Peritoneal macrophages were isolated and cultured from early stage burnt mice. NO production and inducible NO synthase (iNOS) expression in the macrophages were checked by the Greiss method and real-time PCR (TaqMan), respectively. l-Arginine, the substrate of NO producing, or N-monomethyl-l-arginine (l-NMMA), a competing blocker of NOS was administered to the culture, the changes… CONTINUE READING

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