The role of NCAM in remyelination

  title={The role of NCAM in remyelination},
  author={Ayrton Roberto Massaro},
  journal={Neurological Sciences},
The neural cell adhesion molecule (NCAM) is expressed by myelinating precursor cells in neonatal mouse spinal cord and by remyelinating cells after chemically induced demyelination in adult mouse. It shows tempting suggestions about its possible involvement in the reparative mechanisms and the remyelination processes that take place in multiple sclerosis (MS). In fact, its levels progressively increase in the cerebrospinal fluid (CSF) of acute MS patients subjected to steroid treatment… CONTINUE READING


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