The role of NCAM in auditory fear conditioning and its modulation by stress: a focus on the amygdala.

@article{Bisaz2010TheRO,
  title={The role of NCAM in auditory fear conditioning and its modulation by stress: a focus on the amygdala.},
  author={Reto Bisaz and Carmen Sandi},
  journal={Genes, brain, and behavior},
  year={2010},
  volume={9 4},
  pages={353-64}
}
Chronic stress in rodents was shown to induce structural shrinkage and functional alterations in the hippocampus that were linked to spatial memory impairments. Effects of chronic stress on the amygdala have been linked to a facilitation of fear conditioning. Although the underlying molecular mechanisms are still poorly understood, increasing evidence highlights the neural cell adhesion molecule (NCAM) as an important molecular mediator of stress-induced structural and functional alterations… CONTINUE READING