The role of LRRK2 in inflammatory bowel disease

@article{Liu2012TheRO,
  title={The role of LRRK2 in inflammatory bowel disease},
  author={Zhifeng Liu and Michael J Lenardo},
  journal={Cell Research},
  year={2012},
  volume={22},
  pages={1092-1094}
}
LRRK2 was recently identified as a major susceptibility gene for Crohn's disease (CD) by genome-wide association studies (GWAS). LRRK2 deficiency in mice confers enhanced susceptibility to experimental colitis. In this research highlight, we discuss the current understanding of LRRK2 in the context of colitis, and postulate the future directions. 

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 15 references

Similar Papers

Loading similar papers…