The role of IL-21 in immunity and cancer.

@article{Davis2015TheRO,
  title={The role of IL-21 in immunity and cancer.},
  author={Matthew R. Davis and Ziwen Zhu and Dwayne M Hansen and Qian Bai and Yujiang Fang},
  journal={Cancer letters},
  year={2015},
  volume={358 2},
  pages={
          107-114
        }
}
Interleukin-21 (IL-21), produced predominantly by CD4+ T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cytokines. It has been implicated in many immunological processes and has been linked to autoimmune diseases, allergies and other inflammatory diseases. In recent years, the role for IL-21 in the pathogenesis of cancer has also been extensively studied. In this review, we will discuss recent advances concerning the role of IL-21 in… CONTINUE READING

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