The role of IL-13 in helminth-induced inflammation and protective immunity against nematode infections.

@article{Finkelman1999TheRO,
  title={The role of IL-13 in helminth-induced inflammation and protective immunity against nematode infections.},
  author={Fred D. Finkelman and Thomas A. Wynn and Debra D. Donaldson and Joseph J. Urban},
  journal={Current opinion in immunology},
  year={1999},
  volume={11 4},
  pages={
          420-6
        }
}
Helminth infections induce the production of type 2 cytokines, which contribute both to expulsion of the worms and inflammatory responses that can either protect or damage the host. Although IL-4 has been considered the most critical cytokine for both inflammation and protective immunity, recent observations indicate that IL-13 - a related cytokine - can have equal or even greater importance than IL-4 in inflammatory responses and host protection against infection. 
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