The role of IL-12 and TNF-alpha in AIDP and AMAN.

  title={The role of IL-12 and TNF-alpha in AIDP and AMAN.},
  author={Hongxin Deng and Xinke Yang and Tao Jin and Jian Wu and L-S Hu and M-H Chang and X Sun and A. R. Adem and Bengt Winblad and Jie Zhu},
  journal={European journal of neurology},
  volume={15 10},
BACKGROUND Acute inflammatory demyelinating polyradiculoneuropathy (AIDP) and acute motor axonal neuropathy (AMAN) have been described as two major subtypes of Guillain-Barré syndrome (GBS); however, the possible difference of their immune-inflammatory pathogenesis remains unclear. METHODS In this study, by using FACS and enzyme-linked immunosorbent assays analyses, the role of Th1 cytokines tumour necrosis factor-alpha (TNF-alpha), interleukin-12 (IL-12) and their receptors on peripheral… CONTINUE READING


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