The role of FOXP3 in disease progression in colorectal cancer patients

@inproceedings{Grimmig2013TheRO,
  title={The role of FOXP3 in disease progression in colorectal cancer patients},
  author={Tanja Grimmig and Mia Kim and Christoph Thomas Germer and Martin Gasser and Ana Maria Waaga-Gasser},
  booktitle={Oncoimmunology},
  year={2013}
}
The transcription factor forkhead box P3 (FOXP3) has been identified as a marker of CD4+CD25+ regulatory T cells and is a key determinant of their immunosuppressive functions. FOXP3 has indeed been shown to limit antitumor immune responses during tumor progression. In addition, by expressing FOXP3, tumor cells may evade effector T-cell responses. 

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