The role of Epstein–Barr virus in cancer

@article{Pattle2006TheRO,
  title={The role of Epstein–Barr virus in cancer},
  author={Samuel B. Pattle and Paul J. Farrell},
  journal={Expert Opinion on Biological Therapy},
  year={2006},
  volume={6},
  pages={1193 - 1205}
}
  • S. Pattle, P. Farrell
  • Published 18 October 2006
  • Biology, Medicine
  • Expert Opinion on Biological Therapy
Epstein–Barr virus (EBV), discovered > 40 years ago from a Burkitt’s lymphoma biopsy, was the first virus to be directly associated with human cancer. EBV has two distinct life cycles in the human host; a lytic form of infection that produces new infectious virions, and a latent form of infection that allows the virus to persist in a dormant state for the lifetime of the host. EBV has evolved a life cycle that mimics the natural differentiation pathway of antigen-activated B cells, giving the… 

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