The role of DNA methylation as biomarkers in the clinical management of lung cancer.

@article{Fleischhacker2013TheRO,
  title={The role of DNA methylation as biomarkers in the clinical management of lung cancer.},
  author={M. D. W. Wolfgang Fleischhacker and Dimo Dietrich and Volker Liebenberg and John K. Field and Bernd H. Schmidt},
  journal={Expert review of respiratory medicine},
  year={2013},
  volume={7 4},
  pages={363-83}
}
It is now widely accepted that cancer is caused by complex interactions between genetic and epigenetic factors and the environment. Only in the last 20 years, DNA methylation has been recognized as an epigenetic mechanism, which plays a major role during the development and progression of cancers. Accordingly, DNA methylation profiling provides a useful source for biomarkers in distinct clinical questions; for example, risk stratification, diagnosis, staging, prognosis and therapy-response… CONTINUE READING
Highly Cited
This paper has 37 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Similar Papers

Loading similar papers…