The role of DIF-1 signaling in Dictyostelium development.


We have constructed a mutant blocked in the biosynthesis of DIF-1, a chlorinated signal molecule proposed to induce differentiation of both major prestalk cell types formed during Dictyostelium development. Surprisingly, the mutant still forms slugs retaining one prestalk cell type, the pstA cells, and can form mature stalk cells. However, the other major… (More)


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@article{Thompson2000TheRO, title={The role of DIF-1 signaling in Dictyostelium development.}, author={C. R. Thompson and Robert R Kay}, journal={Molecular cell}, year={2000}, volume={6 6}, pages={1509-14} }