The role of Ca2+/calmodulin-stimulable adenylyl cyclases as molecular coincidence detectors in memory formation
@article{Mons1999TheRO, title={The role of Ca2+/calmodulin-stimulable adenylyl cyclases as molecular coincidence detectors in memory formation}, author={Nicole Mons and J. L. Guillou and Robert Jaffard}, journal={Cellular and Molecular Life Sciences CMLS}, year={1999}, volume={55}, pages={525-533} }
Abstract. Evidence from systems as diverse as mollusks, insects and mammals has revealed that adenylyl cyclase, cyclic adenosine 3′,5′-monophosphate (cAMP) cascade, cAMP-dependent protein kinases and their substrates are required for the cellular events underlying the short-term and long-term forms of memory. In Aplysia and Drosophila models, the coincident activation of independent paths converge to produce a synergistic activation of Ca2+/calmodulin-stimulable adenylyl cyclase, thereby…
59 Citations
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