The role of CO(2) and central chemoreception in the control of breathing in the fetus and the neonate.


Central chemoreception is active early in development and likely drives fetal breathing movements, which are influenced by a combination of behavioral state and powerful inhibition. In the premature human infant and newborn rat ventilation increases in response to CO(2); in the rat the sensitivity of the response increases steadily after ∼P12. The premature… (More)
DOI: 10.1016/j.resp.2010.04.009