The role of CD4 T cell help for CD8 CTL activation.

@article{Zhang2009TheRO,
  title={The role of CD4 T cell help for CD8 CTL activation.},
  author={Sheng Zhang and Hongjun Zhang and Jian-dong Zhao},
  journal={Biochemical and biophysical research communications},
  year={2009},
  volume={384 4},
  pages={405-8}
}
CD4 T cells play an important role in the initiation and persistence of CD8 T cells responses. In this review, we report on and evaluate the mechanisms by which CD4 T cells contribute to activation of CD8 T cells and the signal pathways of the down-streaming events after CD4 T cell help.