The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis.

@article{Uhrig2007TheRO,
  title={The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis.},
  author={Joachim F Uhrig and Moola Mutondo and Ilona Andrea Zimmermann and Michael J. Deeks and Laura M Machesky and Philipp Thomas and Silke Uhrig and Claudia Rambke and Patrick J. Hussey and Martin H{\"u}lskamp},
  journal={Development},
  year={2007},
  volume={134 5},
  pages={967-77}
}
The actin-nucleating ARP2-ARP3 complex controls cell shape in plants in many different cell types. Its activity is controlled by a multimeric complex containing BRK1 (also known as HSPC300), NAP1, SRA1, ABI and SCAR/WAVE. In this study, we focus on the function of the five putative SCAR homologues in Arabidopsis and we provide biochemical evidence that AtSCAR2 can activate the ARP2-ARP3 complex in vitro. Among the single mutants, mutations in only AtSCAR2 result in a subtle or weak phenotype… CONTINUE READING