The role of Alu elements in the cis-regulation of RNA processing

@article{Daniel2015TheRO,
  title={The role of Alu elements in the cis-regulation of RNA processing},
  author={Chammiran Daniel and Mikaela Behm and Marie {\"O}hman},
  journal={Cellular and Molecular Life Sciences},
  year={2015},
  volume={72},
  pages={4063-4076}
}
The human genome is under constant invasion by retrotransposable elements. The most successful of these are the Alu elements; with a copy number of over a million, they occupy about 10 % of the entire genome. Interestingly, the vast majority of these Alu insertions are located in gene-rich regions, and one-third of all human genes contains an Alu insertion. Alu sequences are often embedded in gene sequence encoding pre-mRNAs and mature mRNAs, usually as part of their intron or UTRs. Once… Expand
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