The role of Akt (protein kinase B) and protein kinase C in ischemia-reperfusion injury.

@article{Zhao2016TheRO,
  title={The role of Akt (protein kinase B) and protein kinase C in ischemia-reperfusion injury.},
  author={Ethan Y. Zhao and Aslan Efendizade and Lipeng Cai and Yuchuan Ding},
  journal={Neurological research},
  year={2016},
  volume={38 4},
  pages={
          301-8
        }
}
Stroke is a leading cause of long-term disability and death in the United States. Currently, tissue plasminogen activator (tPA), is the only Food and Drug Administration-approved treatment for acute ischemic stroke. However, the use of tPA is restricted to a small subset of acute stroke patients due to its limited 3-h therapeutic time window. Given the limited therapeutic options at present and the multi-factorial progression of ischemic stroke, emphasis has been placed on the discovery and use… CONTINUE READING
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