The role of ABC transporters in progression and clinical outcome of colorectal cancer.

@article{Hlavat2012TheRO,
  title={The role of ABC transporters in progression and clinical outcome of colorectal cancer.},
  author={Ivona Hlavat{\'a} and Beatrice Moheln{\'i}kov{\'a}-Duchoňov{\'a} and Radka V{\'a}clav{\'i}kov{\'a} and Vaclav Liska and Pavel Pitule and Petr Novak and Jan Brůha and Ondrej Vycital and Lubo{\vs} Holubec and Vladislav Tře{\vs}ka and Pavel Erik Vodicka and Pavel Soucek},
  journal={Mutagenesis},
  year={2012},
  volume={27 2},
  pages={
          187-96
        }
}
Worldwide, colorectal cancer (CRC) is the third most common cancer, with the highest mortality rates occurring in Central Europe. The use of chemotherapy to treat CRC is limited by the inter-individual variability in drug response and the development of cancer cell resistance. ATP-binding cassette (ABC) transporters play a crucial role in the development of resistance by the efflux of anticancer agents outside of cancer cells. The aim of this study was to explore transcript levels of all human… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 71 CITATIONS

FILTER CITATIONS BY YEAR

2012
2019

CITATION STATISTICS

  • 7 Highly Influenced Citations

  • Averaged 12 Citations per year over the last 3 years

  • 11% Increase in citations per year in 2018 over 2017

References

Publications referenced by this paper.
SHOWING 1-10 OF 63 REFERENCES

Similar Papers

Loading similar papers…