The role of 99mTc-labelled glucosamine (99mTc-ECDG) in the evaluation of rheumatic joint disease: a screening experience

  title={The role of 99mTc-labelled glucosamine (99mTc-ECDG) in the evaluation of rheumatic joint disease: a screening experience},
  author={Socrates Angelides and Manal El-Mashaleh and Marienne Anagnostou and G. Howe and David Spencer and Vijay Kumar and Nicholas Manolios},
  journal={Nuclear Medicine Communications},
ObjectivesWe investigated the localization pattern of a novel imaging agent, 99mTc-labelled glucosamine (ECDG), in a variety of rheumatic conditions. Materials and methodsSixteen patients were recruited into the study, with either active rheumatoid arthritis or osteoarthritis. 99mTc-ECDG was prepared in-house and patients received 400 MBq intravenously; thereafter, static images were acquired 15 min, 2 h and 4 h later, using a dual-head Siemens e-cam. Images were interpreted by an experienced… 
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