The role of 3′-untranslated region (3′-UTR) mediated mRNA stability in cardiovascular pathophysiology

@article{Misquitta2001TheRO,
  title={The role of 3′-untranslated region (3′-UTR) mediated mRNA stability in cardiovascular pathophysiology},
  author={Christine Misquitta and V R Iyer and Eva S. Werstiuk and Ashok Kumar Grover},
  journal={Molecular and Cellular Biochemistry},
  year={2001},
  volume={224},
  pages={53-67}
}
Knowledge of transcription and translation has advanced our understanding of cardiac diseases. Here, we present the hypothesis that the stability of mRNA mediated by the 3′-untranslated region (3′-UTR) plays a role in changing gene expression in cardiovascular pathophysiology. Several proteins that bind to sequences in the 3′-UTR of mRNA of cardiovascular targets have been identified. The affected mRNAs include those encoding β-adrenergic receptors, angiotensin II receptors, endothelial and… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 127 REFERENCES

HNS, a nuclear-cytoplasmic shuttling sequence in HuR.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1998
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Endothelial dysfunction in hypertension.

  • Journal of hypertension. Supplement : official journal of the International Society of Hypertension
  • 1996
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Alterations of beta-adrenoceptor-G-protein-regulated adenylyl cyclase in heart failure

M Bohm
  • Mol Cell Biochem
  • 1995
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

Vascular beta-adrenoceptor function in hypertension and in ageing.

  • Canadian journal of physiology and pharmacology
  • 2000
VIEW 5 EXCERPTS