The role of 2,4,5-trihydroxyphenylalanine in melanin biosynthesis.

@article{Graham1977TheRO,
  title={The role of 2,4,5-trihydroxyphenylalanine in melanin biosynthesis.},
  author={Doyle G. Graham and Peter W. Jeffs},
  journal={The Journal of biological chemistry},
  year={1977},
  volume={252 16},
  pages={5729-34}
}
Both 3,4-dihydroxyphenylalanine and 2,4,5-trihydroxyphenylalanine were oxidized with periodate and mushroom tyrosinase to determine whether the latter compound is an intermediate in melanin biosynthesis. Matrix analysis of the spectra obtained with a rapid scan spectrophotometer and comparison of the spectra of quinone intermediates with model quinones… CONTINUE READING