The role aortic chemoreceptors during severe CO hypoxia.

  title={The role aortic chemoreceptors during severe CO hypoxia.},
  author={Charles Edward King and Stephen M. Cain and Christopher K. Chapler},
  journal={Canadian journal of physiology and pharmacology},
  volume={63 5},
The importance of aortic chemoreceptors in the circulatory responses to severe carbon monoxide (CO) hypoxia was studied in anesthetized dogs. The aortic chemoreceptors were surgically denervated in eight dogs prior to the induction of CO hypoxia, with nine other dogs serving as intact controls. Values for both whole body and hindlimb blood flow, vascular resistance, and O2 uptake were determined prior to and at 30 min of CO hypoxia in the two groups. Arterial O2 content was reduced 65% using an… CONTINUE READING