The risk of maternal obesity to the long‐term health of the offspring

@article{OReilly2013TheRO,
  title={The risk of maternal obesity to the long‐term health of the offspring},
  author={James R. O'Reilly and Rebecca M. Reynolds},
  journal={Clinical Endocrinology},
  year={2013},
  volume={78}
}
The prevalence of maternal obesity has risen dramatically in recent years, with approximately one in five pregnant women in the UK now classed as obese (body mass index ≥ 30 kg/m2) at antenatal booking. Obesity during pregnancy has been hypothesized to exert long‐term health effects on the developing child through ‘early life programming’. While this phenomenon has been well studied in a maternal undernutrition paradigm, the processes by which the programming effects of maternal obesity are… 
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The state-of-the-art evidence supporting the possibility that adverse metabolic postnatal outcomes such as IR in the offspring of pregnancies with MO and/or excessive GWG may be related to intrauterine activation of ER stress response is summarized.
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