The ribulose monophosphate pathway substitutes for the missing pentose phosphate pathway in the archaeon Thermococcus kodakaraensis.

@article{Orita2006TheRM,
  title={The ribulose monophosphate pathway substitutes for the missing pentose phosphate pathway in the archaeon Thermococcus kodakaraensis.},
  author={Izumi Orita and Takaaki Sato and Hiroya Yurimoto and Nobuo Kato and Haruyuki Atomi and Tadayuki Imanaka and Yasuyoshi Sakai},
  journal={Journal of bacteriology},
  year={2006},
  volume={188 13},
  pages={
          4698-704
        }
}
The ribulose monophosphate (RuMP) pathway, involving 3-hexulose-6-phosphate synthase (HPS) and 6-phospho-3-hexuloisomerase (PHI), is now recognized as a widespread prokaryotic pathway for formaldehyde fixation and detoxification. Interestingly, HPS and PHI homologs are also found in a variety of archaeal strains, and recent biochemical and genome analyses have raised the possibility that the reverse reaction of formaldehyde fixation, i.e., ribulose 5-phosphate (Ru5P) synthesis from fructose 6… CONTINUE READING

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Genomic organization and biochemistry of the ribulose monophosphate pathway and its application in biotechnology

Hiroya Yurimoto, Nobuo Kato, Yasuyoshi Sakai
  • Applied Microbiology and Biotechnology
  • 2009
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