• Biology, Medicine
  • Published in Anticancer research 2002

The retinoid-inducible gene I: effect on apoptosis and mitogen-activated kinase signal pathways.

@article{Huang2002TheRG,
  title={The retinoid-inducible gene I: effect on apoptosis and mitogen-activated kinase signal pathways.},
  author={Shiang-Long Huang and Rong-Yaun Shyu and Ming-Yang Yeh and Shun-Yuan Jiang},
  journal={Anticancer research},
  year={2002},
  volume={22 2A},
  pages={
          799-804
        }
}
BACKGROUND The retinoid-inducible gene I (RIG1), belonging to the family of type II tumor suppressor genes, was isolated from human gastric cancer cells treated with all-trans retinoic acid. The activity of the RIG1 gene was investigated in this study. MATERIALS AND METHODS HtTA cervical and TSGH9201 gastric cancer cells were transiently transfected with expression vectors that synthesized RIG1-myc or RIG1-EGFP fusion protein. Cell growth was analyzed by measuring the incorporation of… CONTINUE READING

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