The retinoblastoma protein-binding region of simian virus 40 large T antigen alters cell cycle regulation in lenses of transgenic mice.

@article{Fromm1994TheRP,
  title={The retinoblastoma protein-binding region of simian virus 40 large T antigen alters cell cycle regulation in lenses of transgenic mice.},
  author={Laurie Fromm and William Shawlot and Karen M Gunning and Janet S Butel and Paul Overbeek},
  journal={Molecular and cellular biology},
  year={1994},
  volume={14 10},
  pages={6743-54}
}
Regulation of the cell cycle is a critical aspect of cellular proliferation, differentiation, and transformation. In many cell types, the differentiation process is accompanied by a loss of proliferative capability, so that terminally differentiated cells become postmitotic and no longer progress through the cell cycle. In the experiments described here, the ocular lens has been used as a system to examine the role of the retinoblastoma protein (pRb) family in regulation of the cell cycle… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
34 Extracted Citations
57 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 34 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 57 references

A simple and rapid method for detection of apoptosis in human cells

  • R. Sager
  • Nucleic Acids Res .
  • 1992

Similar Papers

Loading similar papers…