The retinoblastoma protein: functions beyond the G1-S regulator.

Abstract

Retinoblastoma protein (pRB) is functionally inactivated in a large number of tumors including retinoblastoma, osteosarcoma, small-cell lung carcinoma, as well as bladder, breast and prostate cancers. The best known role of pRB in preventing cancer is inhibition of cell cycle progression by controlling the exit from the cell cycle into G0/G1. In addition… (More)

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Cite this paper

@article{Uchida2012TheRP, title={The retinoblastoma protein: functions beyond the G1-S regulator.}, author={Chiharu Uchida}, journal={Current drug targets}, year={2012}, volume={13 13}, pages={1622-32} }