The retinoblastoma-like protein p130 is involved in the determination of reserve cells in differentiating myoblasts

@article{Carnac2000TheRP,
  title={The retinoblastoma-like protein p130 is involved in the determination of reserve cells in differentiating myoblasts},
  author={Gilles Carnac and Lluis Fajas and Aurore L’honor{\'e} and Claude Sardet and Ned J. C. Lamb and Anne Fernandez},
  journal={Current Biology},
  year={2000},
  volume={10},
  pages={543-546}
}
During skeletal muscle differentiation, a subset of myoblasts remains quiescent and undifferentiated but retains the capacity to self-renew and give rise to differentiating myoblasts [1] [2] [3]: this sub-population of muscle cells was recently termed 'reserve cells' [3]. In order to characterise genes that can regulate the ratio between reserve cells and differentiating myoblasts, we examined members of the retinoblastoma tumor suppressor family - Rb, p107 and p130 - an important family of… CONTINUE READING

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