The retinitis pigmentosa GTPase regulator, RPGR, interacts with the delta subunit of rod cyclic GMP phosphodiesterase.

@article{Linari1999TheRP,
  title={The retinitis pigmentosa GTPase regulator, RPGR, interacts with the delta subunit of rod cyclic GMP phosphodiesterase.},
  author={M. Linari and M. Ueffing and F. Manson and A. Wright and T. Meitinger and J. Becker},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1999},
  volume={96 4},
  pages={
          1315-20
        }
}
  • M. Linari, M. Ueffing, +3 authors J. Becker
  • Published 1999
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
Recently, the retinitis pigmentosa 3 (RP3) gene has been cloned and named retinitis pigmentosa GTPase regulator (RPGR). The amino-terminal half of RPGR is homologous to regulator of chromosome condensation (RCC1), the nucleotide exchange factor for the small GTP-binding protein Ran. In a yeast two-hybrid screen we identified the delta subunit of rod cyclic GMP phosphodiesterase (PDEdelta) as interacting with the RCC1-like domain (RLD) of RPGR (RPGR392). The interaction of RPGR with PDEdelta was… Expand
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References

SHOWING 1-10 OF 40 REFERENCES
Biochemical Characterization and Subcellular Localization of the Mouse Retinitis Pigmentosa GTPase Regulator (mRpgr)*
  • 83
  • PDF
Cloning and gene structure of the rod cGMP phosphodiesterase delta subunit gene (PDED) in man and mouse
  • 18
  • PDF
Mutation spectrum of the gene encoding the beta subunit of rod phosphodiesterase among patients with autosomal recessive retinitis pigmentosa.
  • 291
  • PDF
Deficient Geranylgeranylation of Ram/Rab27 in Choroideremia (*)
  • 203
  • PDF
...
1
2
3
4
...