The reticulons: a family of proteins with diverse functions

  title={The reticulons: a family of proteins with diverse functions},
  author={Yvonne S Yang and Stephen M Strittmatter},
  journal={Genome Biology},
  pages={234 - 234}
The reticulon family is a large and diverse group of membrane-associated proteins found throughout the eukaryotic kingdom. All of its members contain a carboxy-terminal reticulon homology domain that consists of two hydrophobic regions flanking a hydrophilic loop of 60-70 amino acids, but reticulon amino-terminal domains display little or no similarity to each other. Reticulons principally localize to the endoplasmic reticulum, and there is evidence that they influence endoplasmic reticulum… CONTINUE READING