The results, indications, and physiology of posteroventral pallidotomy for patients with Parkinson's disease.

@article{Iacono1995TheRI,
  title={The results, indications, and physiology of posteroventral pallidotomy for patients with Parkinson's disease.},
  author={Robert Paul Iacono and Fumio Shima and Russell R. Lonser and Sandra M Kuniyoshi and George Maeda and Sh. Yamada},
  journal={Neurosurgery},
  year={1995},
  volume={36 6},
  pages={1118-25; discussion 1125-7}
}
In the past, stereotactic surgical intervention for Parkinson's disease was considered indicated only in those patients with active motor manifestations that were refractory to pharmacological therapy, manifestations such as tremor, rigidity, dystonia, and dyskinesia. With the reintroduction and refinement of Leksell's posteroventral pallidotomy, both akinetic and hyperkinetic symptoms are now amenable to surgical treatment. We have analyzed the results of 126 patients who underwent either… CONTINUE READING