The response to sulpiride in social anxiety disorder: D2 receptor function
@article{Bell2013TheRT, title={The response to sulpiride in social anxiety disorder: D2 receptor function}, author={Caroline J Bell and Shamina Bhikha and Helen C. Colhoun and Frances A. Carter and Chris M Frampton and Richard J. Porter}, journal={Journal of Psychopharmacology}, year={2013}, volume={27}, pages={146 - 151} }
Some previous studies have suggested that patients with social anxiety disorder (SAD) have a hypoactive central dopaminergic system. Supporting this there have been reports from neuroimaging studies of reduced striatal D2 receptor binding in subjects with SAD. The aim of this study was to investigate D2 receptor sensitivity in patients with SAD compared with a group of matched, healthy controls using a neuroendocrine challenge with the selective D2 antagonist, sulpiride. D2 receptor function…
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