The response of human neutrophils to a chemotactic tripeptide (N-formyl-methionyl-leucyl-phenylalanine) studied by microcinematography.

@article{Maher1984TheRO,
  title={The response of human neutrophils to a chemotactic tripeptide (N-formyl-methionyl-leucyl-phenylalanine) studied by microcinematography.},
  author={J Maher and Joel Martell and Brian Brantley and E B Cox and James E. Niedel and W F Rosse},
  journal={Blood},
  year={1984},
  volume={64 1},
  pages={221-8}
}
  • J Maher, Joel Martell, +3 authors W F Rosse
  • Published 1984 in Blood
A quantitative microcinematographic technique for the measurement of cellular motion in response to chemical influences is described. The data are analyzed by using a magnetic digitizer connected to a computer, permitting comparison of several characteristics of such motion. When human granulocytes are placed in a gradient of formyl-methionyl-leucyl-phenylalanine (fMLP) (concentration 10(-6)-10(-8) mol/L) against buffer, the motion of the cells is increased in velocity (chemokinesis) and is… CONTINUE READING