The response of "de novo" Parkinson's disease patients to bromocriptine in a "low and slow" regimen is predictive for prognosis.

@article{Sampaio1995TheRO,
  title={The response of "de novo" Parkinson's disease patients to bromocriptine in a "low and slow" regimen is predictive for prognosis.},
  author={Christina Sampaio and Teresa Coelho and Alexandre Castro-Caldas and A Bastos-Lima and Antonin Levy},
  journal={Journal of neural transmission. Supplementum},
  year={1995},
  volume={45},
  pages={197-202}
}
It is possible that Bromocriptine only determines a complete antiparkinson effect in a subset of P.D. patients that have a good dopaminergic reserve. Our study intent to demonstrate that a good short-term response to Bromocriptine used in a "low and slow" regimen is a marker of long term good prognosis. We studied a series of 36 sequential "de novo" P.D. patients treated with Bromocriptine in a "low and slow" regimen. The principal end-point was the introduction of Levodopa. "Good prognosis… CONTINUE READING