The resistance of fibrin-stimulated tissue plasminogen activator to inactivation by a class PAI-2 inhibitor (minactivin).

@article{Leung1987TheRO,
  title={The resistance of fibrin-stimulated tissue plasminogen activator to inactivation by a class PAI-2 inhibitor (minactivin).},
  author={Ken Leung and J A Byatt and Ross Wentworth Stephens},
  journal={Thrombosis research},
  year={1987},
  volume={46 6},
  pages={755-66}
}
Solid phase fibrin was an efficient stimulator of the tissue-type plasminogen activator (t-PA), and the plasmin produced could be detected by colorimetric assay of the soluble phase above the fibrin. However the fibrin-stimulated activity of t-PA was not inhibited by minactivin. This result was in contrast to that obtained with poly-D-lysine (PL) stimulated… CONTINUE READING