The reproductive-cell cycle theory of aging: An update

@article{Atwood2011TheRC,
  title={The reproductive-cell cycle theory of aging: An update},
  author={C. Atwood and R. Bowen},
  journal={Experimental Gerontology},
  year={2011},
  volume={46},
  pages={100-107}
}
  • C. Atwood, R. Bowen
  • Published 2011
  • Medicine, Biology, Engineering
  • Experimental Gerontology
The Reproductive-Cell Cycle Theory posits that the hormones that regulate reproduction act in an antagonistic pleiotrophic manner to control aging via cell cycle signaling; promoting growth and development early in life in order to achieve reproduction, but later in life, in a futile attempt to maintain reproduction, become dysregulated and drive senescence. Since reproduction is the most important function of an organism from the perspective of the survival of the species, if reproductive-cell… Expand
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