The replenishment of the juxtaglomerular renin store after temporary renin depletion

@article{Riedel2004TheRO,
  title={The replenishment of the juxtaglomerular renin store after temporary renin depletion},
  author={B. Riedel and O. Bucher and L. Peters-Haefeli and N. Baechtold-Fowler and G. Peters},
  journal={Pfl{\"u}gers Archiv},
  year={2004},
  volume={347},
  pages={125-135}
}
SummaryRenal cortical and plasma renin activities and the electron microscopic appearance of juxtaglomerular epitheloid cells were investigated in the unclamped renin-depleted kidney of rats with two-kidney-Goldblatt hypertension after removal of the clamped kidney. Within 24 h the renal renin content fell to still lower values, on the 2d day, it rose to one half its normal value, on the 7th day it reached its control value. Renin activity of plasma did not significantly differ from zero until… Expand
Renin release by renin-depleted rats following hypotensive haemorrhage and anesthetics
TLDR
The renin depleted rat may be a useful model for the study of the role of the renin angiotensin system in phenomena such as blood pressure compensation following hypotensive haemorrhage and drinking induced by beta-adrenoreceptor agonists. Expand

References

SHOWING 1-10 OF 31 REFERENCES
Die Ultrastruktur des Juxtaglomerulären Apparates des Meerschweinchens
TLDR
In the Macula densa highly developed enlargements of the basal infoldings of the plasma membrane — “basal labyrinthe” — as well as of the intercellular spaces are described for the first time, which can possibly be interpreted as the morphological equivalent of a high degree of absorption activity. Expand
The development and ultrastructure of the juxtaglomerular cell granule.
  • L. Barajas
  • Biology, Medicine
  • Journal of ultrastructure research
  • 1966
TLDR
Crystalline protogranules appear more abundant in the granular cells from rat and human kidneys with narrowed renal arteries, which could be related to increased synthesis of the secretory product which is thought to be renin. Expand
INTRACELLULAR TRANSPORT OF SECRETORY PROTEINS IN THE PANCREATIC EXOCRINE CELL
TLDR
Investigation of the secretory cycle of the guinea pig pancreas by cell fractionation procedures applied to pancreatic slices incubated in vitro provides direct evidence that secretory proteins are transported from the cisternae of the rough ER to condensing vacuoles via the small vesicles of the Golgi complex. Expand
Plasma renin activity in renal hypertensive rats
TLDR
The results suggest that the plasma renin activity in rats with renal hypertension induced by partially constricting one renal artery and leaving the contralateral kidney untouched is not necessarily augmented, compatible with observations in hypertensive humans with unilateral renal artery stenosis. Expand
Studies on the Genesis of the Juxtaglomerular Cell Granule
TLDR
During this period strong evidence has accumulated that renin is present in the granular cell of the JG complex and that the amount contained therein varies under different physiological and pathological conditions. Expand
Zur elektronenmikroskopischen Untersuchung der juxtaglomerulären Spezialeinrichtungen der Niere
  • O. Bucher, E. Reale
  • Biology
  • Zeitschrift für Zellforschung und Mikroskopische Anatomie
  • 2004
TLDR
The ultrastructure of the epithelioid cells suggests that they have an active metabolism and, according to all evidence, a secretory function. Expand
Zur elektronenmikroskopischen Untersuchung der juxtaglomerulären Spezialeinrichtungen der Niere
  • O. Bucher, E. Reale
  • Medicine
  • Zeitschrift für Zellforschung und Mikroskopische Anatomie
  • 2004
TLDR
The intertubular space is poor in cells; the various “interstitial cells”, often rich in ergastoplasm, are yet to be studied in detail. Expand
Renin suppression by DOC and NaCl in the rat.
TLDR
The results suggest that the nonanesthetized rat is a good subject for physiologic and pharmacologic studies of the renin-angiotensin system. Expand
[The ultrastructure of the juxtaglomerular apparatus of the guinea pig].
  • B. Riedel, O. Bucher
  • Biology, Medicine
  • Zeitschrift fur Zellforschung und mikroskopische Anatomie
  • 1967
TLDR
In unserem Untersuchungsgut finden wir hin und wieder einige wenige, wahrscheinlich Renin enthaltende Granula (Abb. 1–4). Expand
Renin-Aktivität in Nieren ohne „Renin-Granula“
Nach einer Erkl/~rung fiir die abwechselnde Anund Abwesenheit des geschlechtsspezifisehen Untersehiedes der Hexobarbitalnarkose suchend, wurde u . a . auch nach Unterschieden in Milieufaktoren (z. B.Expand
...
1
2
3
4
...