The repertoire of equine intestinal α-defensins

@inproceedings{Bruhn2009TheRO,
  title={The repertoire of equine intestinal α-defensins},
  author={Oliver Bruhn and Sven Paul and Jens Tetens and Georg Erwin Thaller},
  booktitle={BMC Genomics},
  year={2009}
}
Defensins represent an important class of antimicrobial peptides. These effector molecules of the innate immune system act as endogenous antibiotics to protect the organism against infections with pathogenic microorganisms. Mammalian defensins are classified into three distinct sub-families (α-, β- and θ-defensins) according to their specific intramolecular disulfide-bond pattern. The peptides exhibit an antimicrobial activity against a broad spectrum of microorganisms including bacteria and… CONTINUE READING
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