The repair of double-strand breaks in plants: mechanisms and consequences for genome evolution.

@article{Puchta2005TheRO,
  title={The repair of double-strand breaks in plants: mechanisms and consequences for genome evolution.},
  author={Holger Puchta},
  journal={Journal of experimental botany},
  year={2005},
  volume={56 409},
  pages={1-14}
}
The efficient repair of double-strand breaks (DSBs) in genomic DNA is important for the survival of all organisms. In recent years, basic mechanisms of DSB repair in somatic plant cells have been elucidated. DSBs are mainly repaired by non-homologous end-joining (NHEJ). The repair can be associated with deletions, but also insertions due to copying genomic sequences from elsewhere into the break. Species-specific differences of NHEJ have been reported and an inverse correlation of deletion size… CONTINUE READING
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