The reorganization and reactivation of hippocampal maps predict spatial memory performance

@article{Dupret2010TheRA,
  title={The reorganization and reactivation of hippocampal maps predict spatial memory performance},
  author={D. Dupret and J. O’Neill and Barty Pleydell-Bouverie and J. Csicsvari},
  journal={Nature neuroscience},
  year={2010},
  volume={13},
  pages={995 - 1002}
}
The hippocampus is an important brain circuit for spatial memory and the spatially selective spiking of hippocampal neuronal assemblies is thought to provide a mnemonic representation of space. We found that remembering newly learnt goal locations required NMDA receptor–dependent stabilization and enhanced reactivation of goal-related hippocampal assemblies. During spatial learning, place-related firing patterns in the CA1, but not CA3, region of the rat hippocampus were reorganized to… Expand
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