The renin axis and vasoconstriction volume analysis for understanding and treating renovascular and renal hypertension.

@article{Laragh1975TheRA,
  title={The renin axis and vasoconstriction volume analysis for understanding and treating renovascular and renal hypertension.},
  author={John H. Laragh and Jean E. Sealey and Fritz R. B{\"u}hler and Edwin Darracott Vaughan and Hans R. Brunner and Haralambos Gavras and Leslie Baer},
  journal={The American journal of medicine},
  year={1975},
  volume={58 1},
  pages={
          4-13
        }
}
Information defining the renin-angiotension-aldosterone axis as a control system concurrently regulating salt balance and blood pressure has been applied to reexamine the role of renin in experimental and clinical forms of renovascular and renal hypertension, and thence to develop criteria for differentiating these entities. Experimentally, there are two models of renovascular hypertension; one is characterized by excess renin with reduced sodium (vasoconstrictor form) and the other by excess… CONTINUE READING

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