The renin-angiotensin system: a target of and contributor to dyslipidemias, altered glucose homeostasis, and hypertension of the metabolic syndrome.

@article{Putnam2012TheRS,
  title={The renin-angiotensin system: a target of and contributor to dyslipidemias, altered glucose homeostasis, and hypertension of the metabolic syndrome.},
  author={Kelly Putnam and Robin Shoemaker and Frederique B. Yiannikouris and Lisa A. Cassis},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2012},
  volume={302 6},
  pages={H1219-30}
}
The renin-angiotensin system (RAS) is an important therapeutic target in the treatment of hypertension. Obesity has emerged as a primary contributor to essential hypertension in the United States and clusters with other metabolic disorders (hyperglycemia, hypertension, high triglycerides, low HDL cholesterol) defined within the metabolic syndrome. In addition to hypertension, RAS blockade may also serve as an effective treatment strategy to control impaired glucose and insulin tolerance and… CONTINUE READING
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