The renal antihypertensive endocrine function: its relation to cytochrome P-450.

@article{Muirhead1989TheRA,
  title={The renal antihypertensive endocrine function: its relation to cytochrome P-450.},
  author={E. Muirhead and L. W. Byers and J. Capdevila and B. Brooks and J. Pitcock and P. Brown},
  journal={Journal of hypertension},
  year={1989},
  volume={7 5},
  pages={
          361-9
        }
}
Unclipping the Goldblatt hypertensive rat lowers the blood pressure by cells in the renal papilla, the renomedullary interstitial cells (RIC), secreting a hormone that is part of a vasodilator system. A vasodilator, termed medullipin I, can be extracted from the renal papilla. Medullipin I and the renal venous effluent following unclipping have identical biologic properties. Medullipin I appears to be the agent secreted by the kidney following unclipping. Both medullipin I and the renal venous… Expand
Medullopressin: A New Pressor Activity from the Renal Medulla
Anatomy of the renal interstitium.
...
1
2
...