The remission of rheumatoid arthritis during pregnancy

@article{stensen2007TheRO,
  title={The remission of rheumatoid arthritis during pregnancy},
  author={Monika {\O}stensen and Peter M. Villiger},
  journal={Seminars in Immunopathology},
  year={2007},
  volume={29},
  pages={185-191}
}
Rheumatoid arthritis (RA) is an autoimmune disease that is favorably influenced by pregnancy but relapses after delivery. A variety of circulating factors has been considered as candidates for inducing gestational improvement of RA; however, the factors/pathways responsible remain still elusive. This review discusses recent research on the effect of pregnancy on RA with a focus on immunregulation, cytokine secretion, HLA antigens, microchimerism, and innate immunity. The complex hormonal and… 

Tables from this paper

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TLDR
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TLDR
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TLDR
Pregnancy in RA women is a common situation and most pregnant patients experience a remission, closely related to a switch from Th1 to Th2 immune responses and to a decreased production of proinflammatory cytokines, at least in part supported by the changes of the hormonal profile in pregnancy.
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