The reliability of parameters obtained by fitting of (1)H NMRD profiles and (17)O NMR data of potential Gd(3+)-based MRI contrast agents.

Abstract

Synthetic variable temperature (1)H NMRD profiles and (17)O NMR relaxation and shift data were generated with a model based on the Solomon-Bloembergen-Morgan and Freed theories and then fitted simultaneously or individually. The effects of the fitting procedure and of experimental uncertainties on the resulting best-fit parameters were investigated. The… (More)
DOI: 10.1002/cmmi.1677

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