The relevance of the DNA index and proliferation rate in the grading of benign and malignant soft tissue tumors.

@article{Kroese1990TheRO,
  title={The relevance of the DNA index and proliferation rate in the grading of benign and malignant soft tissue tumors.},
  author={M C Kroese and Derek H Rutgers and I S Wils and J. A. M. Van Unnik and Paul J. M. Roholl},
  journal={Cancer},
  year={1990},
  volume={65 8},
  pages={1782-8}
}
The relevance of the DNA index (DI) to malignancy grading and the relationships between mitotic score, Ki-67 score, and the proportion of cells in the G1-phase (G1PF) of the cell cycle, as proliferative indicators, were investigated in benign (n = 8) and malignant (n = 46) soft tissue sarcomas. Although DI was not found to be related to the histology of the sarcomas, it was associated with malignancy grade, i.e., 14%, 25%, 42%, and 86% of benign, Grade 1, Grade 2, and Grade 3, respectively had… CONTINUE READING